From: hubermanlab
The visual system is an intricate network that allows individuals to perceive and interact with the world around them. At its core, this system translates photons—the basic particles of light—into visual experiences, ultimately leading to the perception of color and form. In a recent discussion between Professor Andrew Huberman and Dr. David Berson on the Huberman Lab Podcast, a detailed exploration of how this process unfolds was presented.

The Eye as a Sensor

The initial stage of visual perception begins when photons enter the eye. They are first detected by the retina—a thin layer at the back of the eye that functions like the film of a camera or the sensitive chip in a digital sensor. Within the retina, there are specialized cells called photoreceptors, which consist of rods and cones. Rods are primarily responsible for vision in low light, whereas cones are crucial for color vision.

Role of Photoreceptors

Color vision is primarily mediated by three types of cone cells, each sensitive to different wavelengths of light, which correspond to the colors red, green, and blue. Dr. Berson elaborates, stating that these different types of cones absorb light at different frequencies, which are then processed by the nervous system to produce the experience of color [00:10:06].

The Transformation to Neural Signals

The transformation of light to electrical signals occurs in the first layer of the retina. Here, the light is absorbed by photoreceptors containing specialized proteins tasked with this conversion. Different types of these proteins are tuned to absorb different light frequencies, setting the stage for color vision [00:12:11].

Perceptual Experience of Color

The perception of color arises when the brain decodes the differences in signals from the three types of cones, allowing for the wide spectrum of colors humans can perceive. Interestingly, not all creatures perceive color in the same way. While humans typically have three types of cones, many animals, such as dogs, have only two, making their color perception akin to certain forms of human color blindness [00:15:10].

Unpacking Color Vision

Color vision depends on the comparative processing of inputs from the three types of cones. For instance, a sense of ‘redness’ results from a particular pattern of activity across the three cone types. The nervous system processes these patterns to generate the perception of specific colors [00:12:25].

Philosophical and Biological Considerations

A fascinating point raised during their discussion was whether individuals perceive colors like red or blue in the same way. Dr. Berson suggests this question is philosophical as much as it is scientific, given that although the underlying biological mechanisms appear consistent across individuals, personal experience remains subjective [00:12:53].

Probing Further into Photopigments

Dr. Berson introduced the concept of the “fly eye,” referencing an unusual photopigment called melanopsin found in different layers of the retina. This pigment absorbs light directly and is seen as a more primitive feature retained from an evolutionary past, linking our vertebrate eyes with those of invertebrates like flies [00:20:54].

Applications and Implications

The understanding of human color vision is not just a scientific endeavor but also carries significant practical implications. It affects everything from the design of screens and lighting to interventions for visual impairments and color blindness. Moreover, the discussion between Huberman and Berson highlights ongoing research into the nuances of visual perception, an area poised to advance with insights into genetic and neuronal variability among individuals [01:36:02].

In sum, the conversion of light into color is a complex but exquisitely organized process, involving the seamless integration of physical, cellular, and neurological mechanisms to produce the vibrant visual experiences so fundamental to human life.