From: hubermanlab
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Hydration plays a crucial role in maintaining both physical and cognitive health. Dehydration, even at mild levels, can significantly impair body functions and diminish mental performance. This article explores the scientific insights into how hydration affects health, based on a comprehensive discussion led by Dr. Andrew Huberman from the “Huberman Lab Podcast.”

Understanding Hydration

Hydration refers to the intake and absorption of fluids by the body. The primary route for hydration is through the consumption of water, although other beverages contribute as well. Once ingested, water is absorbed through the digestive tract and delivered to various cells and organs via the bloodstream.

Signs of Dehydration

Dehydration is not always easy to detect, especially in mild forms. Here are some general indicators:

  • Skin Elasticity: Pinching the skin on the back of your hand and observing if it returns quickly to its original form can indicate hydration levels, although this is not entirely reliable.
  • Urine Color: Darker urine can be a sign of dehydration, but this varies with diet and supplement intake.
  • Physical and Cognitive Impairments: Even slight dehydration (about 2%) can reduce physical endurance, strength, cognitive functions, memory, focus, and creativity [01:03:00].

General Guidelines

Dr. Andrew Huberman suggests ingesting approximately 8 ounces (about 240 milliliters) of fluid every hour for the first 10 hours after waking. This amounts to about 80 ounces or 2.4 liters per day, which adequately supports bodily functions under non-strenuous conditions [01:08:02].

During Exercise

For those engaging in physical activities, hydration needs increase. The “Galpin Equation” provides a useful guideline: divide your body weight in pounds by 30, which gives you the number of ounces of fluid to consume approximately every 15-20 minutes during exercise. For metric users, this translates to roughly 2 milliliters per kilogram of body weight for the same period [01:12:18].

Environmental Considerations

Factors like heat and humidity can increase fluid requirements. In such conditions, it’s advisable to up the fluid intake by 50% to 100% to account for additional losses through sweat [01:15:02].

Hydration and Cognitive Function

Hydration is closely linked to alertness and cognitive performance. Sufficient fluid intake facilitates cellular functions and helps regulate mood and focus. Mechanically, water intake exerts pressure on body receptors, triggering signals that heighten alertness and improve mental clarity [01:21:00].

Sympathetic Nervous System and Fluid Balance

Adequate hydration stimulates the sympathetic nervous system, responsible for increasing wakefulness and readiness. When well-hydrated, the mechanical and chemical signals from body tissues enhance energy and cognitive capabilities. Water movement through aquaporin channels across cell membranes is central to these benefits, aiding in quicker and more efficient hydration [01:12:14].

Conclusion

Adequate hydration is fundamental for maintaining physical endurance and cognitive prowess, promoting energy levels, and managing stress responses. By keeping fluids balanced in the body, you support sustenance and enhance quality of life across various activities and environmental conditions. Always be mindful of personal needs, and adjust your fluid intake based on activity level and environmental factors. By doing so, you leverage hydration as a powerful tool for health and performance optimization.